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| Product Name | CFL2, 1-166aa, Human, His tag, E Coli |
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| Description | MW: 20.9kDa (186a), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. CFL2 protein belongs to the actin-binding proteins ADF family that contains 1 ADF-H domain. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Defects in CFL2 are the cause of nemaline myopathy type 7 (NEM7). Recombinant human CFL2 protein, fused to His-tag at N-terminus, was expres |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Cofilin-2; NEM7] |
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| Gene, Accession, CAS # | CFL2, Gene ID: 1073, Accession: NP_068733 |
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| Catalog # | MBS204139 |
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| Order / More Info | CFL2, 1-166aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Agrawal P.B., et al. (2007) Am. J. Hum. Genet. 80:162-167; Gillett GT, et al. (1996). Ann. Hum. Genet. 60 (Pt 3): 201-11 |
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