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| Product Name | Notch1, Recombinant, Mouse,Fc (Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300) |
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| Description | Purity >95% (SDS-PAGE). Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. Sequence: The extracellular domain of mouse Notch1 (aa 19-488) (12 epidermal growth factor-like (EGF) repeats) is fused at the C-terminus to the Fc portion of human IgG1. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45099 |
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| Order / More Info | Notch1, Recombinant, Mouse,Fc (Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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