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| Product Name | Notch Reporter BioAssay™ Kit (cAMP/PKA Pathway) |
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| Description | Notch Pathway Reporter BioAssay™ kit is designed for monitoring the activity of the Notch signaling pathway in cultured cells. The kit contains a transfection-ready expression vector for NOTCH1 that has a deletion of the entire extracellular domain (Notch1deltaE). Inside the cells, the NOTCH1 DE can be cleaved by upsilon-secretase and active NOTCH1 NICD is released into the nucleus. The kit also contains CSL (CBF1/RBP-Jk) luciferase reporter vector, which is a Notch pathway-responsive reporter. This reporter contains the firefly luciferase gene under the control of multimerized CSL responsive elements upstream of a minimal promoter. The CSL (CBF1/RBP-Jk) reporter is premixed with constitutively expressing Renilla (sea pansy) luciferase vector, which serves as an internal positive control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively expressing Renilla luciferase vector as a negative control. The non-induc |
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| Size | 500 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 171935 |
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| Order / More Info | Notch Reporter BioAssay™ Kit (cAMP/PKA Pathway) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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