产品名称 SAHA (Vorinostat ) from ARBOR ASSAYS, INC.
产品货号 P004-250MG
产品价格 现货询价,电话:010-67529703
产品规格 250 mg
产品品牌 ARBOR ASSAYS, INC.
产品概述
产品详情
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Product NameSAHA (Vorinostat )
DescriptionSAHA (suberoylanilide hydroxamic acid, Vorinostat, Zolinza™) is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. Sirt activator based on a dihydropyridine structural scaffold. EC150 (effective concentration able to increase enzyme activity by 150%) is 1 uM for Sirt1, 25 uM for Sirt2, and 50 uM for Sirt3. The compound is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. SAHA inhibits class I and class II HDACs at around 50 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 uM.
Size250 mg
Concentrationn/a
ApplicationsActivator or Inhibitor
Other Namessuberoylanilide hydroxamic acid, Vorinostat, Zolinza
Gene, Accession, CAS #n/a
Catalog #P004-250MG
Price
Order / More InfoSAHA (Vorinostat ) from ARBOR ASSAYS, INC.
Product Specific Referencesn/a
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