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| Product Name | GCN5, Recombinant, Human, aa727-837, His-Tag (Histone Acetyltransferase KAT2A) |
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| Description | Highly Purified (~99%). KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]. Source: Recombinant protein corresponding to aa727-837 from human GCN5, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~14.1kD AA Sequence: MHHHHHHLKDPDQLYTTLKNLLAQIKSHPSAW PFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSR YYVTRKLFVADLQRVIANCREYNPPDSEYCRCA SALEKFFYFKLKEGGLIDK Applications: Suitable for use in the study of bromodomain binding assays, screening inhibitors, and selectivity profiling. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_021078, SwissProt: Q92830 |
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| Catalog # | 298410 |
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| Order / More Info | GCN5, Recombinant, Human, aa727-837, His-Tag (Histone Acetyltransferase KAT2A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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