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| Product Name | GCN5, Recombinant, Human, His-Tag |
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| Description | Purity ~95% (SDS-PAGE). GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4. Source: Recombinant protein corresponding to human GCN5, fused to a His-tag, expressed in Sf21 cells. Biological Activity: ~200-300ng are required for standard HAT assay |
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| Size | 2ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GCN5, Recombinant, Human, His-Tag (GCN5L2, Histone Acetyltransferase GCN5, General Control of Amino Acid Synthesis Protein 5-like 2, Histone Acetyltransferase KAT2A, HsGCN5, Lysine Acetyltransferase 2A, STAF97, HGCN5) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207207 |
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| Order / More Info | GCN5, Recombinant, Human, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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