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| Product Name | BMP-2, Active, Recombinant, Human, aa283-396 (Bone morphogenetic protein 2, BMP-2A) |
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| Description | Purity ~90% (SDS-PAGE). BMP-2 (Bone morphogenetic protein 2) is multi-functional growth factor that belongs to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility. Source: Recombinant protein corresponding to aa283-396 from human BMP-2, expressed in E. coli. Molecular Weight: ~13kD (115aa) Biological Activity: Measured by its ability to induce alkaline phosphatase production using ATDC5 mouse chondrogenic cells, the ED50 for this effect is <57ng/ml. Activity Assay: 1. Cell line: ATDC5 (mouse chondrogenic cell) 2. Maintenance Condition: 10% FBS RPMI 1640 3. Assay medium: 1% FBS RPMI 1640 4. Cell Density: 2x10e4 cells/well (96 well plate, final volume 100ul) 5. S |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001191 |
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| Catalog # | 351107 |
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| Order / More Info | BMP-2, Active, Recombinant, Human, aa283-396 (Bone morphogenetic protein 2, BMP-2A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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