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| Product Name | BMP8A, Recombinant, Human, (BMP-8A, Bone Morphogenetic Protein 8A) |
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| Description | Purity ~95% (SDS-PAGE). MP-8, also known as osteogenic protein 2 (OP-2), was first isolated from a hippocampal library in a screen to identify relatives of BMP-7/OP-1. BMPs are a family of structurally and functionally related proteins and represent a subfamily of the transforming growth factor b (TGF-b) superfamily. BMPs are involved in a wide range of processes including embryogenesis, tissue morphogenesis, cell differentiation and migration, and tumorigenesis. Cellular responses to BMPs are mediated by hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMP-8a and BMP-8b, produced from separate genes, share 98% aa sequence identity in human but only 74% in mouse within the mature regions. Human BMP-8a is synthesized as a 402aa precursor protein that is cleaved between aa263 and aa264 to release the C-terminal mature protein. Mature human BMP-8a shares 90% and 68% aa sequence identity with mouse mature BMP-8a and -8b, respectively. BMP-8a is expressed |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: AAP74559 |
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| Catalog # | B2553-35M |
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| Order / More Info | BMP8A, Recombinant, Human, (BMP-8A, Bone Morphogenetic Protein 8A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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