| 产品详情 |
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| Product Name | Ubiquitin Aldehyde, Recombinant, Human (rh-Ubiquitin Aldehyde) |
| Description | Purity ~95% (HPLC, SDS-PAGE). The C-terminal glycine carboxyl of Ubiquitin is synthetically modified to an aldehyde. Ubiquitin Aldehyde (Ub-H) is useful in the stabilization of ubiquitin-protein conjugates in vitro, enhancing their accumulation in cell lysates and tissue extracts. Inhibition of deubiquitinylating enzyme activity by Ub-H can be used to identify and confirm such activity and to determine the inhibition kinetics for a particular enzyme. Recommended concentration for maximal inhibition is 2-5uM. Co-crystallization of ubiquitin aldehyde with specific deubiquitinylating enzymes (the inhibitor mimics the natural ubiquitin substrate) has also been used to probe enzyme: substrate interactions. Source: Recombinant corresponding to human Ubiquitin Aldehyde expressed in E. coli. Molecular Weight: ~8.5kD Biological Activity: Ki = 2.5nM vs UCH isopeptidase-T |
| Size | 50ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | U1000-06V |
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| Order / More Info | Ubiquitin Aldehyde, Recombinant, Human (rh-Ubiquitin Aldehyde) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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