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| Product Name | PLK1, Recombinant, Human, His-Tag (Polo-like Kinase 1, Serine-Threonine Kinase 13, STPK13) |
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| Description | Purified (~70-90%). PLK1 is a member of the Polo-Like Kinase family that localize to centrosomes or spindle pole bodies and undergo dramatic subcellular relocation during the cell cycle. Deregulated activities of PLKs often result in abnormalities in centrosome duplication, maturation, and/or microtubule dynamics. PLKs also regulate the function of the Golgi complex. Deregulated expression of human PLK1 is strongly correlated with the development of many types of malignancies, and ectopic expression of PLK1 dominant negative protein leads to rapid cell death. Source: Recombinant protein corresponding to human PLK1, fused to His-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~70kD Specific Activity: 20nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_005030 |
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| Catalog # | 500402 |
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| Order / More Info | PLK1, Recombinant, Human, His-Tag (Polo-like Kinase 1, Serine-Threonine Kinase 13, STPK13) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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