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| Product Name | MAPK14, Recombinant, Human, aa1-360 His-Tag |
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| Description | Purity ~90% (SDS-PAGE). MAPK14 (Mitogen-activated protein kinase 14) is a member of the MAP kinase family. MAPK14 is most closely related to p38 MAP kinases (MAPKs). MAPKs are activated primarily in response to inflammatory cytokines and cellular stress, and inhibitors which target the MAPK14 and MAPK11 have shown potential for the treatment of inflammatory disease. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response. Source: Recombinant corresponding to aa1-360 from human MAPK14, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSQERPT FYRQELNKTI WEVPERYQNL SPVGSGAYGS VCAAFDTKTG LRVAVKKLSR PFQSIIHAKR TYRELRLLKH MKHENVIGLL DVFTPARSLE EFNDVYLVTH LMGADLNNIV KCQKLTDDHV QFLIYQILRG LKYIHSADII HRDLKPSNLA VNEDCELKIL DFGLARHTDD EMTG |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MAPK14, Recombinant, Human, aa1-360 His-Tag (Mitogen-activated Protein Kinase 14, MAP Kinase 14, MAPK 14, Cytokine Suppressive anti-inflammatory Drug-binding Protein, CSAID-binding Protein, CSBP, MAP Kinase MXI2, MAX-interacting Protein 2, Mitogen-activated Protein Kinase p38 alpha, MAP Kinase p38 alpha, SAPK2A, CSBP, CSBP1, CSBP2, CSPB1, MXI2) |
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| Gene, Accession, CAS # | Accession: NP_620581 |
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| Catalog # | 29670 |
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| Order / More Info | MAPK14, Recombinant, Human, aa1-360 His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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