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| Product Name | Adiponectin, Recombinant, Mouse (Acrp-30, GBP-28, Apm-1) |
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| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. Adiponectin is an adipose-derived secreted protein containing 236 amino acid residues.nbsp It is relatively abundant in humans and rodents, accounting for about 0.01% of total plasma protein.nbsp The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes.nbsp Disruption of adiponectin in mice causes insulin resistance and neointimal formation.nbsp Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity.nbsp The protective role of adiponectin is attributed to its anti-inflammatory properties (e.g. ability to suppress expression of TNF-beta and class A scavenger receptor in macrophages). Recombinant adiponectin is a multimeric glycoprotein containing amino acids Val-21 to Asn-247 of the adiponectin precursor protein fused to an N-terminal histidine tag.nbsp Monomeric |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143271 |
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| Order / More Info | Adiponectin, Recombinant, Mouse (Acrp-30, GBP-28, Apm-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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