产品详情 |
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Antigenic Specificity | Programmed Cell Death 1 (PDCD1) (aa 21-167) |
Clone | P4F12AT |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 5 µg |
Concentration | n/a |
Applications | ELISA,Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDCD1 is a cell surface membrane protein of the immunoglobulin superfamily. PDCD1 is expressed in pro-B-cells and is thought to have a role in their differentiation. In mice, expression of PDCD1 gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for the PDCD1 gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that the PDCD1 gene product may also be important in T cell function and contribute to the prevention of autoimmune diseasesSynonyms: Programmed cell death protein 1, Protein PD-1, hPD-1, CD279, PDCD1, PD1, SLEB2 |
Immunogen | Anti-human PDCD1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PDCD1 AA 21-167 |
Other Names | CD279|PD-1|PD1|SLEB2|hPD-1|hPD-l|Ly101|Pdc1|tamo |
Gene, Accession # | Gene ID: 5133 |
Catalog # | ABIN808833 |
Price | |
Order / More Info | Programmed Cell Death 1 (PDCD1) (aa 21-167) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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