产品详情 |
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Antigenic Specificity | Nurr1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nurr1 Polyclonal Antibody. Parkinson's disease (PD) is a multifactorial disease that appears to arise from the effects of both genetic and environmental influences. The known genetic factors include multiple genes that have been identified in related parkinsonian syndromes, as well as alpha-synuclein. Genes associated with either PD or Parkinson-related disorders include parkin, DJ-1, ubiquitin C-terminal hydrolase isozyme L1 (UCH-L1), nuclear receptor-related factor 1 (NURR1), and alpha-synuclein. Nurr1 is a transcription factor that is expressed in the embryonic ventral midbrain and is critical for the development of dopamine (DA) neurons. It belongs to the conserved family of nuclear receptors but lacks an identified ligand and is theref |
Immunogen | n/a |
Other Names | Orphan nuclear receptor NR4A2; Orphan nuclear receptor NURR1; NURR1; NGFI-B; TINUR; NR4A2; Immediate-early response protein NOT; NOT; Transcriptionally inducible nuclear receptor |
Gene, Accession # | Entrez: 18227, 4929; Uniprot: P43354, Q06219 |
Catalog # | PA5-13416 |
Price | |
Order / More Info | Nurr1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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