| 产品详情 |
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| Antigenic Specificity | Interleukin 2 Receptor, alpha (IL2RA) |
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| Clone | PC61-5 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1 |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS),Immunoprecipitation (IP),Immunohistochemistry (Frozen Sections) (IHC (fro)),Functional Studies (Func) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD25 (IL2Ralpha, Tac) is a ligand-binding alpha subunit of interleukin 2 receptor (IL2R). Together with beta and gamma subunit CD25 constitues the high affinity IL2R, whereas CD25 alone serves as the low affinity IL2R. CD25 expression rapidly increases upon T cell activation. The 55 kDa CD25 molecule is enzymatically cleaved and shed from the cell surface as a soluble 45 kDa s-Tac, whose concentration in serum can be used as a marker of T cell activation. Expression of CD25 indicates the neoplastic phenotype of mast cells. CD25+ CD4+ FoxP3+ regulatory cells (Treg cells) play a crucial role in the control of organ-specific autoimmune diseases. |
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| Immunogen | B6.1 CTL cell line |
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| Other Names | CD25|HEM45|IDDM10|IL2R|TCGFR|IL2RAC|IL-2RA|Il2r|Ly-43 |
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| Gene, Accession # | Gene ID: 16184 |
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| Catalog # | ABIN1302633 |
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| Price | |
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| Order / More Info | Interleukin 2 Receptor, alpha (IL2RA) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 20037737, 18981144, 12052865, 9166839, 16000396, 18832672, 17101658, 10666272 |
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