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| Product Name | Mouse GDNF Protein (Recombinant) |
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| Description | Purity >95% by SDS-PAGE and HPLC, MW: 17-22 kDa (SDS-PAGE). Glial-Derived Neurotrophic Factor, also known as GDNF and ATF-1, is a neurotrophic factor belonging to the TGF-beta family. It is expressed in both central nervous system (CNS) and non-CNS tissues. GDNF signals through a receptor system composed of a RET and one of the four GFR alpha receptors. It promotes the survival and differentiation of dopaminergic neurons, and increases their high-affinity dopamine uptake. In a mouse Parkinson's Disease model, GDNF has been shown to improve bradykinesia, rigidity, and postural instability. GDNF has also been shown to regulate kidney development, spermatogenesis and affect alcohol consumption. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GDNF, HSCR3, HFB1-GDNF, ATF, HGDNF |
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| Gene, Accession, CAS # | GDNF, Gene ID: 2668 |
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| Catalog # | LS-G27230 |
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| Order / More Info | Mouse GDNF Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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