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| Product Name | MART-1, Recombinant, Human |
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| Description | Highly Purified (~95%). Protein melan-A also known as melanoma antigen recognized by T-cells 1 or MART-1 is a protein that in humans is encoded by the MLANA gene. A fragment of the protein, usually consisting of the nine amino acids 27-35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines. MART-1 or MELAN-A is recognized by autologous T lymphocytes. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Antibodies against the MART-1 are used in the medical specialty of anatomic pathology in order to recognize cells of melanocytic differentiation, useful for the diagnosis of a melanoma. The same name is also used to refer to the gene which cod |
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| Size | 2ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | MART-1, Recombinant, Human (Melanocyte Differentiation-A, Melan-A, Antigen LB39-AAAntigen SK29-AA Protein Melan-A) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209081 |
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| Order / More Info | MART-1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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