产品详情 |
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Antigenic Specificity | TRIP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRIP6 Polyclonal Antibody. TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-kappa-B activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55. |
Immunogen | n/a |
Other Names | tcag7.1300, OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1; OPA-interacting protein 1; TR-interacting protein 6; thyroid hormone receptor interacting protein 6; thyroid receptor-interacting protein 6; zyxin related protein 1 |
Gene, Accession # | Entrez: 22051, 7205; Uniprot: Q15654, Q9Z1Y4 |
Catalog # | PA5-21040 |
Price | |
Order / More Info | TRIP6 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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