| 产品详情 |
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| Antigenic Specificity | TIRAP Tyr86 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TIRAP(Tyr86) Polyclonal Antibody. • Target Background: Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. |
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| Immunogen | KLH conjugated synthetic acetylpeptide derived from human TIRAP around phosphorylation site of Tyr86 [KD(p-Y)DV]. Immunogen Range: 70-95/221 |
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| Other Names | Phosphorylated, phospho-Mal; wyatt; BACTS1; MyD88-2; Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein; TIRAP |
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| Gene, Accession # | Gene ID: 114609, SwissProt: P58753 |
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| Catalog # | bs-7562R |
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| Price | |
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| Order / More Info | TIRAP Tyr86 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Rolf, Nina, et al.(2015) Eur J Immunol. PubMed: 25867213 |
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