| 产品详情 |
| Edit |   |
|---|
| Product Name | RIZ1, Recombinant, Human, aa2-200, GST-tag |
|---|
| Description | Purity ~95% (SDS-PAGE). Retinoblastoma protein-interacting zinc finger protein 1 (RIZ1), also known as PRDM2, is a SAM-dependent histone methyltransferase that specifically methylates histone H3 on lysine 9. RIZ1 contains 8 zinc-finger motifs and 1 PR domain. The RIZ gene encodes two different proteins, RIZ1 and RIZ2. RIZ1 is a tumor suppressor that can arrest the cell cycle and induce apoptosis. RIZ2 however, is a proto-oncoprotein lacking the N-terminal PR domain containing the methyltransferase activity. When RIZ1 is silenced or mutated, the reduced methyltransferase activity can lead to inheritable changes in chromatin methylation and gene expression patterns. Source: Recombinant protein corresponding to aa2-200 from human RIZ1, fused to GST-tag at N-terminal, expressed in E. coli. Molecular Weight: ~49.5kD (aa2-200 + NT GST Tag) |
|---|
| Size | 50ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | RIZ1, Recombinant, Human, aa2-200, GST-tag (KMT8, PRDM2, PR Domain Zinc Finger Protein 2, Retinoblastoma Protein-interacting Zinc Finger Protein) |
|---|
| Gene, Accession, CAS # | PRDM2, Gene ID: 7799, SwissProt: Q13029 |
|---|
| Catalog # | 220232 |
|---|
| Price | |
|---|
| Order / More Info | RIZ1, Recombinant, Human, aa2-200, GST-tag from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|