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Product Name | DSCR1 isoform b, 1-117aa, Human, E.coli |
Description | Purity: > 90% by SDS - PAGE Format: In 20mM Tris 7.5, 0.1M NaCl, 1mM DTT. The Down's syndrome candidate region 1 (DSCR1) protein, encoded by a gene located in the human chromosome 21, interacts with calcineurin and is overexpressed in Down's syndrome patients. DSCR1 Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, possibly affecting central nervous system development. DSCR isoform b is shorter at the N-terminus compared to isoform a. Recombinant human DSCR1 was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Down syndrome candidate region 1, Down syndrome candidate region 1, Down syndrome critical region protein 1, adapt78 protein, calcipressin 1, Calcipressin 1 isoform b, Down syndrome candidate region 1 |
Gene, Accession, CAS # | NP 981962 |
Catalog # | DSR0701 |
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Order / More Info | DSCR1 isoform b, 1-117aa, Human, E.coli from ATGen |
Product Specific References | n/a |
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