| 产品详情 |
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| Antigenic Specificity | CD274 Molecule (CD274) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens. It also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Synonyms: B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1 |
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| Immunogen | Recombinant protein of human CD274 |
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| Other Names | A530045L16Rik|B7h1|Pdcd1l1|Pdcd1lg1|Pdl1|B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1|RGD1566211 |
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| Gene, Accession # | Gene ID: 29126,60533,499342 |
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| Catalog # | ABIN1512699 |
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| Price | |
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| Order / More Info | CD274 Molecule (CD274) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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