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| Product Name | ERO1 Inhibitor I, Erodoxin |
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| Description | Purity ~99% (HPLC). A cell-permeable dinitrobromobenzene compound that acts as a selective inhibitor of yeast Endoplasmic Reticulum Oxidase 1 (ERO1), but has somewhat weaker activity against mouse ERO1a (IC50=400uM). Predicted to form thiol adducts and inhibits ERO1-dependent oxidation of thioredoxin-1 (Trx1) activity in vitro. Shown to cluster with genes involved in protein folding, glycosylation and cell wall biosynthesis, and delay carboxypeptidase Y (CPY) processing to the vacuolar form in wt-yeast cells. Formula: C7H5BrN2O5 Molecular Weight: 277 Solubility: DMSO (100mg/ml) |
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| Size | 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ERO1 Inhibitor I, Erodoxin (Endoplasmic Reticulum Oxidase 1 Inhibitor, 1-Bromo-5-methoxy-2,4-dinitrobenzene) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217347 |
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| Order / More Info | ERO1 Inhibitor I, Erodoxin from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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