产品详情 |
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Antigenic Specificity | Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) |
Clone | 1A10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC),Immunofluorescence (IF),ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age- related neuronal diseases, such as Alzheimer's and Huntington's disease.Synonyms: G3PD, GAPD, MGC88685 |
Immunogen | Purified recombinant fragment of human GAPDH expressed in E. Coli. |
Other Names | CG8893|Dmel\\CG8893|GA3PDH|GADPH|GAP|GAPDH|GAPDH II|GAPDH2|Gapd|Gapdh|Gapdh-2|Gapdh13F|GAPD|g3pd|gapd|GB14798|GAPC-2|GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE C-2|T6J4.17|T6J4_17|glyceraldehyde-3-phosphate dehydrogenase C2|BEST:GH12586|CG12055|Dmel\\CG12055|GAPDH I|GAPDH-1|GAPDH1|GAPDHI|Gapdh-1|Gapdh43E|gadph|gapdh|gapdh-1|gh12586|KNC-NDS6|G3PD|cb609|mg:bb02e05|wu:fb33a10|wu:ft80f05|G3PDH |
Gene, Accession # | Gene ID: 2597 |
Catalog # | ABIN966180 |
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Order / More Info | Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 3027061 |
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