| 产品详情 |
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| Antigenic Specificity | Nrf2 |
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| Clone | 21HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Western Blot: 0.5 -2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Nrf2 Antibody (21HCLC), ABfinity™ Rabbit Oligoclonal. Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription activator which plays a key role in protecting the cell from oxidative stress and inflammation. It is primarily localized in the cytoplasm under normal conditions, but under conditions of oxidative stress, Nrf2 migrates to the nucleus to upregulate expression of genes with ARE (antioxidant response elements) in the promoter region. The upregulated genes include those involved in cellular protection, drug transport, detoxification, and anti-oxidant defense. The protein is ubiquitously expressed in various tissues, with the highest levels found in kidney, muscle, lung, heart, liver, and brain. |
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| Immunogen | n/a |
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| Other Names | E4TF1-60, E4TF1A, NFT2,HEBP1, NRF2A, NF-E2-related factor 2, NFE2-related factor 2, nuclear factor erythroid 2-related factor 2, nuclear factor erythroid-derived 2-like 2 |
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| Gene, Accession # | Entrez: 4780; Uniprot: Q16236 |
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| Catalog # | 710574 |
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| Price | |
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| Order / More Info | Nrf2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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