| 产品详情 |
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| Product Name | OSCAR, Recombinant, Human, aa19-282, His-tag |
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| Description | Purity ~90% (SDS-PAGE). OSCAR, also known as osteoclast-associated immunoglobulin-like receptor isoform 6, is an activating receptor expressed by human myeloid cells. It is a receptor for surfactant protein D that activates TNF-Alpha release from human CCR2+ inflammatory monocytes. It is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells. Its expression is detected specifically in preosteoclasts or mature osteoclasts. It is upregulated on monocytes from rheumatoid arthritis (RA) patients with active disease, and these monocytes show an increased proosteoclastogenic potential. Source: Recombinant protein corresponding to aa19-282 from human OSCAR, fused to His-Tag at C-terminal, expressed in Insect Cell. Molecular Weight: ~29.2kD (270aa) ~40-57kD (SDS-PAGE under reducing conditions) AA |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | OSCAR, Recombinant, Human, aa19-282, His-Tag (OSCAR, PIgR-3, PIGR3, Osteoclast-Associated Immunoglobulin-Like Receptor Isoform) |
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| Gene, Accession, CAS # | Accession: NP_001269278 |
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| Catalog # | 470248 |
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| Order / More Info | OSCAR, Recombinant, Human, aa19-282, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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