| 产品详情 |
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| Product Name | Cadein1 |
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| Description | Purity ~97% (HPLC). A cell-permeable isoquinolinium compound that preferentially induces apoptotic cell death in p53-deficient cancer cells with functional MMR (DNA mismatch repair) system, including HCT116-Ch3/E6, HeLa, HT29, and SW620 (viability <19 %; 4-6uM Cadein1 for 24h), while exhibiting much reduced potency in MMR-/p53+ (RKO and HCT116), MMR-/p53- (DLD-1 and HCT116-E6), and MMR+/p53+ (HCT116-Ch3 and HEK293) cancer cultures (viability = 40 to 92%; 4uM Cadein1 for 24h). Formula: C33H48F2INO2 Molecular Weight: 655.7 Solubility: DMSO (100mg/ml) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cadein1 (1-Pentadecyl-6,7-dimethoxy-2-(2,6-difluorobenzyl)-3,4-dihydroisoquinolium chloride, Cancer-selective Death Inducer 1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217238 |
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| Price | |
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| Order / More Info | Cadein1 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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