| 产品详情 |
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| Antigenic Specificity | Vitronectin Receptor (CD51) |
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| Clone | NKI-M7 (former AMF7) |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | supernatant |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunoprecipitation (IP) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD51 (Cluster of Differentiation 51), known as vitronectin receptor alpha chain, or integrin alphaV is a type I integral membrane glycoprotein. CD51 forms a heterodimer with integrin beta1 (CD29), beta3 (CD61), beta5, beta6, or beta8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its beta chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thrombospondin, osteopontin, fibrinogen, and laminin. CD51, as an adhesion molecule, plays important roles in leukocytes homing and rolling, mediates bone absorption and angiogenesis. CD51 is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN1042464 |
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| Price | |
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| Order / More Info | Vitronectin Receptor (CD51) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 2428758, 2033986 |
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