| 产品详情 |
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| Antigenic Specificity | CD29 (Integrin beta 1) |
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| Clone | eBioHMb1-1 (HMb1-1) |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse, rat |
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| Isotype | IgG |
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| Format | unconjugated, functional grade |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD29 (Integrin beta 1) Monoclonal Antibody (eBioHMb1-1 (HMb1-1)), Functional Grade, eBioscience™. CD29 (beta1 integrin subunit, GPIIa) forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CD49a-f) determining the binding properties of beta1 (VLA) integrins. These integrins mediate cell adhesion to collagen, fibronectin, laminin and other extracellular matrix (ECM) components. This interaction hinders cell death, whereas disruption of anchorage to ECM leads to apoptosis. Decreased expression of most beta1 integrins correlates with acquiring multidrug resistance of tumour cells during selection in presence of antitumour drug. In platelets, translocation of intracellular pool of beta1 integrins |
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| Immunogen | n/a |
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| Other Names | FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB, ITGB1, ITBG1D |
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| Gene, Accession # | Entrez: 16412, 24511; Uniprot: P09055, P49134 |
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| Catalog # | 16-0291-85 |
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| Price | |
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| Order / More Info | CD29 (Integrin beta 1) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18302991, 26380065, 28979820, 28983600, 29185450 |
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