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Antigenic Specificity | Lysosomal-Associated Membrane Protein 1 (LAMP1) |
Clone | H4A3 |
Host Species | Mouse |
Reactive Species | human, nonhuman primate, mouse |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FACS),Western Blotting (WB),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)),Immunocytochemistry (ICC),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2 % of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation. |
Immunogen | Human PBMC |
Other Names | AI196048|CD107a|Lamp-1|LAMPA|LGP120|LEP100 |
Gene, Accession # | Gene ID: 3916,16783 |
Catalog # | ABIN1027703 |
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Order / More Info | Lysosomal-Associated Membrane Protein 1 (LAMP1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 20164232, 22365987, 18713944, 17675468, 17283169, 11485903, 2912382, 16861636 |
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