| 产品详情 |
| Edit |   |
|---|
| Product Name | Fingolimod Hydrochloride |
|---|
| Description | Purity ~98%. Fingolimod (FTY720), a sphingosine 1-phosphate (S1P) analog, is a novel immunosuppressant drug that induces lymphopenia by preventing emergence of lymphocytes from lymph nodes. Fingolimod is a sphingosine-1-phosphate receptor 1 modulator and is in phase III clinical trials for relapsing-remitting multiple sclerosis. Solubility: Soluble in DMSO at 100mg/ml; soluble in ethanol at 100mg/ml; very poorly soluble in water. Up to 25ul of a solution of 13.8mg/ml (40mM) F4513-40 in 100% DMSO can be diluted into 5ml of plain water without precipitation, giving a final concentration of 200uM. In contrast, even a 1:1000 dilution of the same 13.8mg/ml DMSO stock solution into 10mM PBS, pH 7 results in a precipitate. Thus, F4513-40 solubility in PBS is likely to be well below 100uM, perhaps as low as 1-10ug/ml. Either DMSO, ethanol or plain water should be used as the solvent until the final dilution is made into culture medium Elemental Analysis: Calculated: C=66.35% H=9.96% Cl=10.31% |
|---|
| Size | 50mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Fingolimod Hydrochloride (FTY-720A, FTY720, D04187, 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Hydrochloride) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | F4513-40 |
|---|
| Price | |
|---|
| Order / More Info | Fingolimod Hydrochloride from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|