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Antigenic Specificity | Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The enzyme glutamate decarboxylase (GAD) is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid . GAD1 (GAD67) and GAD2 (GAD65) are expressed in nervous and endocrine systems and are thought to be involved in synaptic transmission and insulin secretion , respectively. Autoantibodies against GAD2 may serve as markers for type I diabetes . Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2 . Synonyms: GAD2,GAD65,MGC161605,MGC161607 , |
Immunogen | Recombinant protein of human GAD2 |
Other Names | GAD65|gad65|F12P19.12|F12P19_12|GLUTAMATE DECARBOXYLASE 2|glutamate decarboxylase 2|zgc:112198|6330404F12Rik|GAD(65)|Gad-2 |
Gene, Accession # | Gene ID: 2572,14417,24380 |
Catalog # | ABIN1683609 |
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Order / More Info | Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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