| 产品详情 |
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| Antigenic Specificity | Forkhead Box P3 (FOXP3) |
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| Clone | MF-14 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b |
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| Format | biotin conjugate |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Frozen Sections) (IHC (fro)),Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Forkhead-winged helix P3 (Foxp3), also known as Scurfin or JM2, is a 50-55 kDa transcription factor, originally identified as the gene defective in Scurfy mice. Scurfy mice and humans with similar mutations spontaneously develop autoimmune diseases (IPEX). Resent reports revealed that Foxp3 is expressed in CD4 + CD25 + regulatory T cells (Treg cells), and ectopic expression of Foxp3 in CD4 + Foxp3 - T cells induced a Treg-like phenotype in these cells. Importantly, these reports indicate that Foxp3 is a specific marker for Treg cells. Taken together, Foxp3 is believed to be a crucial regulator of the development and function of Treg cells.Synonyms: Forkhead box protein P3, IPEX, JM2, Scurfin |
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| Immunogen | n/a |
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| Other Names | foxp3|FOXP3|AIID|DIETER|IPEX|PIDX|XPID|JM2|scurfin|sf|RGD1562112 |
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| Gene, Accession # | Gene ID: 20371 |
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| Catalog # | ABIN2853612 |
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| Price | |
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| Order / More Info | Forkhead Box P3 (FOXP3) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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