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| Product Name | NAE1, 1-534aa, Human, His tag, E Coli |
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| Description | MW: 62.7kDa (557aa). Purity >90% by SDS-PAGE. NAE1 (NEDD8-activating enzyme E1 regulatory subunit) belongs to the ubiquitin-activating E1 family. This protein binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. NAE1 participates in a novel ubiquitinylation-related pathway involving the ubiquitin-like molecule NEDD8. Also, this protein |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [NEDD8 activating enzyme E1 subunit 1; A-116A10.1; APPBP1; HPP1; ula-1] |
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| Gene, Accession, CAS # | NAE1, Gene ID: 8883, Accession: NP_003896 |
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| Catalog # | MBS204415 |
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| Order / More Info | NAE1, 1-534aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Chen Y, et al. (2000) J Biol Chem. 275 (12):8929-35.; Bohnsack R.N., et al. (2003) J. Biol. Chem. 278:26823-26830 |
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