| 产品详情 |
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| Antigenic Specificity | ROR gamma (t) |
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| Clone | 4G419 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25-0.5 µg/1x10^6 cells, Western Blot: 5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ROR gamma (t) Monoclonal Antibody (4G419). ROR gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. Reports suggest that ROR gamma is a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR gamma shares 50 to 51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues. |
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| Immunogen | n/a |
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| Other Names | RP11-98D18.11-001, NR1F3, RORG, RZR-GAMMA, RZRG, TOR, RAR-related orphan nuclear receptor variant 2, nuclear receptor ROR-gamma, nuclear receptor RZR-gamma, nuclear receptor subfamily 1 group F member 3, retinoic acid-binding receptor gamma, retinoid-related orphan receptor gamma |
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| Gene, Accession # | Entrez: 19885, 368158, 6097; Uniprot: P51449, P51450 |
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| Catalog # | MA5-16227 |
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| Price | |
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| Order / More Info | ROR gamma (t) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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