| 产品详情 |
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| Antigenic Specificity | ROR gamma (t) |
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| Clone | B2D |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ROR gamma (t) Monoclonal Antibody (B2D), eBioscience™. ROR gamma, a NR1 Thyroid Hormone-Like receptor, has been shown to affect thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. ROR gamma has been shown to promote thymocyte survival by activating the expression of the antiapoptotic protein Bcl-x(L). ROR gamma is also required for the development of lymph nodes and Peyer's patches. It has been shown that ROR gamma t, a thymus-specific isoform of ROR gamma from mouse, inhibits Fas ligand expression and cytokine secretion in immature thymocytes. ROR gamma binds as a monomer to response elements composed of a single core motif, GGTCA, preceded by a 6 bp AT-rich sequence. ROR gamma expression has been documented |
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| Immunogen | n/a |
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| Other Names | MGC129539, NR1F3, RORG, RZR-GAMMA, RZRG, TOR |
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| Gene, Accession # | Entrez: 19885; Uniprot: P51450 |
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| Catalog # | 14-6981-80 |
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| Price | |
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| Order / More Info | ROR gamma (t) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 19029903, 19841181, 21151104, 21600798, 22921335, 23648563, 23690441, 23797094, 23922467, 24336249, 24356888, 24446517, 24552849, 24637841, 25344471, 25347065, 25436972, 25490199, 25501629, 25917102, 25918343, 25963989, 26006007, 26039259, 26912317, 27027355, 27111144, 27312851, 27643438, 28169274, 28560450, 28607488, 29249358 |
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