产品详情 |
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Antigenic Specificity | ROR gamma (t) |
Clone | B2D |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, kappa |
Format | PerCP-eFluor 710 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.25 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ROR gamma (t) Monoclonal Antibody (B2D), PerCP-eFluor 710, eBioscience™. ROR gamma, a NR1 Thyroid Hormone-Like receptor, has been shown to affect thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. ROR gamma has been shown to promote thymocyte survival by activating the expression of the antiapoptotic protein Bcl-x(L). ROR gamma is also required for the development of lymph nodes and Peyer's patches. It has been shown that ROR gamma t, a thymus-specific isoform of ROR gamma from mouse, inhibits Fas ligand expression and cytokine secretion in immature thymocytes. ROR gamma binds as a monomer to response elements composed of a single core motif, GGTCA, preceded by a 6 bp AT-rich sequence. ROR gamma expression ha |
Immunogen | n/a |
Other Names | MGC129539, NR1F3, RORG, RZR-GAMMA, RZRG, TOR |
Gene, Accession # | Entrez: 19885; Uniprot: P51450 |
Catalog # | 46-6981-80 |
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Order / More Info | ROR gamma (t) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19029903, 22921335, 24336249, 25917102, 26523868, 28194010, 28607488, 29249358 |
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