| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | WNT7A |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:5000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | WNT7A Polyclonal Antibody. WNT7A is a Wnt protein that constitute a family of secreted glycoproteins that activate signal transduction pathways to mediate tissue homeostasis, cell fate, cell proliferation, and self-renewal. The canonical signaling pathway is initiated upon Wnt binding to a Frizzled family receptor and an LRP5/LRP6 coreceptor, which leads to activation of the beta-catenin cascade. Non-canonical Wnt signals are activated by binding to a Frizzled family receptor and ROR2 coreceptor. Extensive research has shown that deregulation of these pathways or its components can lead to cancer. Human Wnt-1 is encoded as a 370 amino acid precursor that, upon secretion, is cleaved into a 343 amino acid (42 kDa) mature form. At the amino ac |
|---|
| Immunogen | n/a |
|---|
| Other Names | WNT7A, protein Wnt-7a, proto-oncogene Wnt7a protein, wingless-type MMTV integration site family, member 7A |
|---|
| Gene, Accession # | Entrez: 7476; Uniprot: O00755 |
|---|
| Catalog # | PA5-78227 |
|---|
| Price | |
|---|
| Order / More Info | WNT7A Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|