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Antigenic Specificity | Actin, beta (ACTB) |
Clone | 8F10-G10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | affinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility,structure,and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq,Jul 2008]Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Subunit structure: Polymerization of globular actin(G-actin)leads to a structural filament(F-actin)in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a mRNP granule complex,at least composed of ACTB,ACTN4,DHX9,ERG,HNRNPA1,HNRNPA2B1,HNRNPAB,HNRNPD,HNRNPL,HNRNPR,HNRNPU,HSPA1,HSPA8,IGF2BP1,ILF2,ILF3,NCBP1,NCL,PABPC1,PABPC4,PABPN1,RPLP0,RPS3,RPS3A,RPS4X,RPS8,RPS9,SYNCRIP,TROVE2,YBX1 and untranslated mRNAs. Component of the BAF complex,which includes at least actin(ACTB),ARID1A,ARID1B/BAF250,SMARCA2,SMARCA4/BRG1,ACTL6A/BAF53,ACTL6B/BAF53B,SMARCE1/BAF57 SMARCC1/BAF155,SMARCC2/BAF170,SMARCB1/SNF5/INI1,and one or more of SMARCD1/BAF60A,SMARCD2/BAF60B,or SMARCD3/BAF60C. In muscle cells,the BAF complex also contains DPF3. Found in a complex with XPO6,Ran,ACTB and PFN1. Component of the MLL5-L complex,at least composed of MLL5,STK38,PPP1CA,PPP1CB,PPP1CC,HCFC1,ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2. Interacts with GCSAM. Subcellular location: Cytoplasm>cytoskeletonSequence similarities: Belongs to the actin family. |
Immunogen | Purified recombinant human beta actin protein fragments expressed in E.coli. |
Other Names | beta-actin|ps1tp5bp1|LOC563571|ACTB|A26C1A|A26C1B|act-2|actb|B-actin|LOC100136013|LOC100174883|LOC100304816|A|ACT5C|Ac5C|Act|Act-5C|Act5|Act5c|Actin|Actin/BAP47|Actin5C|BAP47|Bap47|CG4027|Dmel\\CG4027|M32055|T11|act|act 5C|act5C|actin|actin5C|anon-EST:fe2D2|beta-actin/Bap47|cyt5C|l(1)G0009|l(1)G0010|l(1)G0025|l(1)G0079|l(1)G0117|l(1)G0177|l(1)G0245|l(1)G0330|l(1)G0420|l(1)G0486|Bact|BRWS1|PS1TP5BP1|ACT-5|Actx|E430023M04Rik|ACTA1|Beta-actin|B-ACTZF|actba|bact|bactin1|bactzf|wu:fd18f05|POTE2alpha|POTEACTIN |
Gene, Accession # | Gene ID: 728378 |
Catalog # | ABIN1558147 |
Price | |
Order / More Info | Actin, beta (ACTB) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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