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| Product Name | FKBP1B, Recombinant, Human, aa1-108, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). FKBP1B, is a member of the immunophilin protein family which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. Source: Recombinant corresponding to aa1-108 from human FKBP1B, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH RSMGVEIETI SPGDGRTFPK KGQTCVVHYT GMLQNGKKFD SSRDRNKPFK FRIGKQEVIK GFEEGAAQMS LGQRAKLTCT PDVAYGATGH PGVIPPNATL IFDVELLNLE Molecular Weight: ~14.2kD (MALDI-TOF) Enzyme Activity: Specific activity is > 800 nmol/min/mg, and is defined as the amount of enzyme cleaves 1nmole of suc-AAFP-PNA per minute at 37°C in Tris-HCl pH 8.0 using chymotrypsin. |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FKBP1B, Recombinant, Human, aa1-108, His-Tag (Peptidyl-prolyl Cis-trans Isomerase FKBP1B, PPIase FKBP1B, 12.6kD FK506-binding Protein, 12.6kD FKBP, FKBP-12.6, FK506-binding Protein 1B, FKBP-1B, Immunophilin FKBP12.6, Rotamase, h-FKBP-12, FKBP12.6, FKBP1L, FKBP9, OTK4) |
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| Gene, Accession, CAS # | Accession: NP_004107 |
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| Catalog # | F4150-12G |
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| Order / More Info | FKBP1B, Recombinant, Human, aa1-108, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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