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| Product Name | FKBP1B, Recombinant, Human, aa1-108, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B) belongs to the immunophilin protein family which has a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP1B is a cis-trans prolyl isomerase which binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). FKBP1B is extremely similar to the FK506-binding protein 1A. The physiological role of FKBP1B is thought to be in excitation-contraction coupling in cardiac muscle. Source: Recombinant protein corresponding to aa1-108 from human FKBP1B, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~14.2kD (130aa, aa1-108 + NT His Tag) Specific Activity: >300 nmoles/min/mg, Defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA/minute at 25°C in Tris HCl pH 8.0 using chymotrypsin. AA Sequence: MGSSHHHHHH SSGLVPRGSH RSMGVEIETI SPGDGRTFPK KGQTCVVHYT GMLQNGKKFD SSRDRNKPFK FRIGKQEVIK GFEEGAAQMS LGQRAKLTCT PDVAYGATGH PGVIPPNATL |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FKBP1B, Recombinant, Human, aa1-108, His-Tag (Peptidyl-prolyl cis-trans isomerase FKBP1B, FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 169966 |
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| Order / More Info | FKBP1B, Recombinant, Human, aa1-108, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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