Edit |   |
Antigenic Specificity | ARID1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 10 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ARID1B Polyclonal Antibody. Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexe |
Immunogen | n/a |
Other Names | BAF250B, DAN15, KIAA1235, OSA2 |
Gene, Accession # | Entrez: 57492; Uniprot: Q8NFD5 |
Catalog # | IHC-00234-T |
Price | |
Order / More Info | ARID1B Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |