| 产品详情 |
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| Antigenic Specificity | beta-Arrestin 2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | beta-Arrestin 2 Polyclonal Antibody. Beta-arrestin-2, or ARRB2, is an adaptor protein belonging to the arrestin family with an N- arrestin domain and a C- arrestin domain. ARRB2 is a regulatory protein involved in heterotrimeric G protein-coupled receptor desensitization and is known to regulate beta2-adrenergic receptor (beta2AR) function by enhancing beta2AR mediated nuclear translocation of ERK. ARRB2 binds to phosphorylated beta2ARs, thereby causing a significant impairment of their capacity to activate G(S) proteins. Along with AIP4, ARRB2 acts as an endosomal sorting molecule that mediates CXCR4 entry into a degradative pathway. It may also be involved in hormone-specific desensitization of TSH receptors. ARRB2 is a Ca2+ binding prote |
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| Immunogen | n/a |
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| Other Names | beta-arrestin2, SAG, S-Arrestin |
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| Gene, Accession # | Entrez: 216869, 25388, 281638, 409; Uniprot: P29067, P32120, P32121, Q91YI4 |
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| Catalog # | PA1-732 |
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| Price | |
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| Order / More Info | beta-Arrestin 2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 19200235, 19776273 |
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