产品详情 |
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Antigenic Specificity | alpha-1b Adrenergic Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | alpha-1b Adrenergic Receptor Polyclonal Antibody. Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. |
Immunogen | n/a |
Other Names | ADRA1, ALPHA1BAR, alpha-1B adrenergic receptor, alpha-1B adrenoceptor, alpha-1B adrenoreceptor, alpha-1B-adrenergic receptor |
Gene, Accession # | Entrez: 11548; Uniprot: P97717 |
Catalog # | PA5-27120 |
Price | |
Order / More Info | alpha-1b Adrenergic Receptor Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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