| 产品详情 |
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| Antigenic Specificity | GPR182 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GPR182 Polyclonal Antibody. Adrenomedullin (ADM) is a hypotensive peptide that belongs to a peptide superfamily, which includes the calcitonin gene-related peptide (CGRP) and amylin . ADM was originally identified in the adrenal medulla, where it is highly expressed . It is also produced by most contractile cells and is upregulated during sepsis and ischemia. Three distinct receptors have the ability to bind ADM and are designated ADM receptor (also designated L1), RDC-1 and the Calcitonin Receptor-Like Receptor (CRLR) . The CRLR associates with receptor activity-modifying proteins (RAMPs), which determine the specificity of CRLR binding . Co-expression with RAMP1 results in CRLR binding to CGRP, whereas association with RAMP2 or 3 results |
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| Immunogen | n/a |
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| Other Names | G-protein coupled receptor 182; GPR182; ADMR |
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| Gene, Accession # | Entrez: 11318, 11536, 29307; Uniprot: O15218, P31392, P43142 |
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| Catalog # | PA5-75662 |
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| Price | |
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| Order / More Info | GPR182 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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