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| Product Name | Diethylpyrocarbonate (DEPC) |
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| Description | Purity ≥97%. DEPC is a strong nuclease inhibitor, utilizing a mechanism which modifies His and Tyr residues in proteins. Used as a RNase and DNase inhibitor for Molecular Biology solutions. DEPC is a chemical use to inactivate RNase enzymes and is sensitive to moisture and pH. It decomposes at 155°C, to ethanol and carbon dioxide in aqueous solution. DEPC is also sensitive to ammonia, which causes decomposition to urethane, a possible carcinogen. Biochem and Physiological Actions: Inactivates RNase in solution at about 0.1% (v/v), thus protecting RNA against degradation. DEPC is a potent nuclease inhibitor, a 0.1% solution of DEPC is used to inactive RNase. It inhibits the ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose and time dependent manner and increases the Ca2+ permeability of SR vesicles. Purity: ≥97% Appearance: Supplied as a colorless, clear liquid Refractive Index (n20/D): 1.398 (lit.) Boiling Point: 93-94°C/18mmHg (lit.) Density: 1.101g/mL at 25°C (lit |
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| Size | 25ml, 50ml, 100ml |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Diethyloxydiformate; Ethyloxyformic acid anhydride; Diethyl dicarbonate; DEP; DEPC; EC 216-542-8 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | D7900 |
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| Order / More Info | Diethylpyrocarbonate (DEPC) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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