| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | HIPPI |
|---|
| Clone | OTI2G3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | HIPPI Monoclonal Antibody (OTI2G3). Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
|---|
| Immunogen | n/a |
|---|
| Other Names | ESRRBL1, HIPPI, MHS4R2, HIP1 protein interactor, HIP1-interacting protein, dermal papilla-derived protein 8, estrogen-related receptor beta like 1, estrogen-related receptor beta-like protein 1, huntingtin interacting protein-1 interacting protein, intraflagellar transport protein 57 |
|---|
| Gene, Accession # | Entrez: 55081; Uniprot: Q9NWB7 |
|---|
| Catalog # | MA5-25043 |
|---|
| Price | |
|---|
| Order / More Info | HIPPI Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|