| 产品详情 |
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| Antigenic Specificity | HIPPI |
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| Clone | OTI4F6 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HIPPI Monoclonal Antibody (OTI4F6). Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
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| Immunogen | n/a |
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| Other Names | ESRRBL1, HIPPI, MHS4R2, HIP1 protein interactor, HIP1-interacting protein, dermal papilla-derived protein 8, estrogen-related receptor beta like 1, estrogen-related receptor beta-like protein 1, huntingtin interacting protein-1 interacting protein, intraflagellar transport protein 57 |
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| Gene, Accession # | Entrez: 55081; Uniprot: Q9NWB7 |
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| Catalog # | MA5-25044 |
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| Price | |
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| Order / More Info | HIPPI Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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