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| Product Name | Von Willebrand Factor, Factor VIII Free, Human (vWF, Factor VIII Related Antigen) |
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| Description | Purity ≥95% pure by SDS-PAGE under reducing conditions. Consists of large multimers as determined by electrophoresis in SDS/agarose gels. Multimeric Structure of von Willebrand Factor: Each vWF monomer (Mr = 260kD) contains a Factor VIII binding site near the NH2-terminal end of the molecule. The monomers are joined end-to-end (NH2 to NH2 and COOH to COOH) by disulfide bonds to form large multimers. The mature multimers can bind one Factor VIII molecule per monomeric subunit. Von Willebrand Factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation (1-8). The mature plasma protein is composed of apparently identical subunits (Mr = 260kD) which are held together by disulfide bonds. The circulating vWF molecule ranges in size from dimers (Mr = 520kD) to extremely large multimers (Mr > 10,000,000). During normal hemostasis, the larger multimers of vWF are responsible for facilitating platelet plug formation by forming a bridge between p |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | V2651 |
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| Order / More Info | Von Willebrand Factor, Factor VIII Free, Human (vWF, Factor VIII Related Antigen) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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