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| Product Name | Von Willebrand Factor (vWF) BioAssay™ ELISA Kit (Antibodies only) |
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| Description | Matched Matched-Pair Antibody Set suitable for use in sandwich ELISA for the detection of human von Willebrand Factor Antigen (vWF). von Willebrand Factor (vWF, previously referred to as Factor VIII Related Antigen) is a large adhesive protein produced in endothelial cells and megakaryocytes. There are two critical functions of vWF. The first being its involvement in the process of platelet adhesion and aggregation through interaction with platelet receptor glycoprotein Ib. The second being the binding and stabilization of Factor VIII (anti-hemophilic factor) for secretion and transport in plasma. The vWF precursor protein is synthesized with a 95kD propeptide (also known as vWF antigen-II). The propeptide is believed to be involved in the intracellular multimerization of the vWF subunits. The mature vWF multimers are then packed into storage organelles within the cell (Weibel-Palade bodies). After which, the propeptide is cleaved and released. vWF circulates as multimers of disulfide |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | V2700-09 |
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| Order / More Info | Von Willebrand Factor (vWF) BioAssay™ ELISA Kit (Antibodies only) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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